Arcoxia® is one of the most effective drugs on the market at this time for the treatment of inflammatory diseases of the joints and musculoskeletal system.
The active ingredient of the drug is etoricoxib, which belongs to the group of coxibs. The pharmacological actions of this drug include the following:
The primary purpose of the drug is the inhibition of COX-2 activity by a particular mechanism, which prevents the biosynthesis of prostaglandins and mediators of inflammation. The active substance does not damage the mucous membrane of the digestive tract and does not affect the functional activity of platelets.
Indications for use
Doctors usually prescribe Arcoxia® in the following cases:
- Rheumatoid arthritis
- Inflammation of the joints of various etymologies
- Gouty arthritis with inflammation and pain manifestations
- Surgical operations in dentistry
Dosing and administration
Arcoxia® is available in the form of tablets with a dosage of 60 mg, 90 mg, or 120 mg and is taken orally. Patients should take the drug with a small amount of water.
The dosage of Arcoxia® is determined by the physician and typically depends on the diagnosis for which the drug is prescribed, as follows:
- In the case of rheumatoid arthritis, a single dose of 90 mg is taken once a day.
- Up to 120 mg per day is recommended for the treatment of acute gouty arthritis.
- Up to 90 mg per day is used after dental operations as necessary.
- Not more than 60 mg per day is taken in the treatment of osteochondrosis and other diseases if the patient has hepatic insufficiency.
In most cases, the duration of treatment with Arcoxia® is eight days.
Side effects include:
- Negative manifestations in the respiratory system presenting in the form of dyspnea, cough, and/or nosebleeds; in exceptional cases, there may be bronchospasm.
- With a negative effect on the nervous system, dizziness, confusion, weakness, taste disturbance, and tinnitus are possible. In rare cases, there may be hallucinations.
- When side effects impact the cardiovascular system, an increased heart rate appears and arterial blood pressure rises. Furthermore, among rare but noted manifestations, doctors may observe congestive heart failure, atrial fibrillation, hot flashes, and cerebral circulation.
- There may be muscle cramps, myalgia, and/or arthralgia.
- The drug can cause various disorders in the gastrointestinal system, including gastritis, ulcer bleeding, belching, vomiting, and bloating.
The drug is not recommended for use in patients with lactose intolerance, bronchial asthma, and/or inflammatory bowel pathology.
It is forbidden to use this medication and its analogs during pregnancy and breastfeeding. It should not be prescribed sans the presence of vital indications in patients younger than 18 years of age.
Another contraindication to its use is the individual intolerance of any component that is part of the drug.
Furthermore, Arcoxia® is contraindicated in patients who have been diagnosed with the following pathologies:
- Bleeding in the gastrointestinal tract
- Liver dysfunction
- Polyposis of the nose
- Arterial hypertension